This
page is from a collection of
materials indexed at this website
arising from an investigation and
campaign by Brian Deer in The
Sunday Times of London over
serious risks and side-effects
from this antibiotic, marketed
under many names, including Septran,
Septrin, Septra, Bactrim, Bactrim
DS, Septra DS, Sulfatrim, SMZ/TMP
and co-trimoxazole.
Go to
side-effects homepage
Below is page 19
of a selection of mail to this
website. Start with selected
letters to The Sunday Times at this link. Feel
free to share your own
experience, which may help
others. If this site helps you,
or a loved one, please consider
making a donation to keep
it going
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BACTRIM:
23 November 2005
Hello,
Brian I am so glad to have come across
your wed site for this situation. My 24
year old sister was prescribed Bactrim
for a staph infection. The infection
cleared up very quickly. Her doctor put
her in the hospital for IV antibiotics.
She was told to go home and continue to
take the Bactrim. She became so ill for
the last four weeks we have had to bring
her to the ER several times and today she
is still in the hospital. All blood work
shows no sign of the staph infection
which started out on the lower part of
stomach area. When it started three weeks
ago she begin with severe pain through
out her body and feeling very sick. She
had the shakes she is still numb from her
neck up and can not taste anything. Her
blood pressure when she stands up is 60
that is why she is still in the hospital.
A cardiologist is seeing and treating her
for that. She is not in as much pain as
before but still very exhausted just to
sit up in bed is hard for her. They have
ran so many test MRI, EKG, blood work,
urinalysis every test has come up
nothing. They do not see any reason why
she is still so ill and we have mentioned
the medication to them and no one seems
to think this is still the reaction
causing the problem. Could you please let
me know if people are this ill for this
long with reactions to this nightmare of
a medication that needs to be taken off
of the market so no one else or their
family has to go through this. She was a
perfectly healthy 24 year old with no
known health issues. She is getting very
depressed and has anxiety quite often.
Please share any info you have on how
long this could take. Also if you know of
any one that had trouble with extremely
low blood pressure and very fast pulse
rate... Everyday we wake up and say maybe
today will be the turning point for her
but this has not happened yet. She now
has seizure type shakes in the morning
that she can not control...this maybe be
due to the blood pressure meds he is
giving her to bring her pressure up.
Please help us maybe understand this
better and it this will go away..
Thank
you
Dawn
CO-TRIMOXAZOLE:
28 November 2005
Dear
Brian
I
had my first experience with this
antibiotic in July this year. The day
after finishing a 7 day course I awoke
about 4am with a grumbling stomach. That
was July 24th 2005. It is now November
28th and my stomach still grumbles but I
have also had fatigue, and trembling legs
something like RLS. I am 59 year old and
was prescribed these for bronchitis. Some
days in August and September my brain
didnt function properly and it did not
feel like I was real. I have always been
quite a fit fellow and tramp the hills
and mountains but find now I dont have
the energy I manage about 5 hours at work
until I get fatigued and my stomach
growls and legs tremble.
Kindest
regards
Glen
G, Christchurch, NZ
SEPTRA:
29 November 2005
Brian
-
I
have read many of the e-mails on your
website...I can empathize with Denise
from Manhattan, as my wife was prescribed
Septra, by a nurse practitioner, for a
supposed urinary tract infection. We have
since discovered by a regular visit to
the OBGYN, because my wife is 8 months
pregnant, that the lab results actually
didn't show a UTI - and that the OBGYN
says the hospitals sometimes do this -
prescribe something just to get you out
of there (we went to the ER, because we
thought it was premature labor). The
thought of a UTI came about because my
wife was urinating about every 30 mins.
Well, needless to say, the OBGYN has
taken my wife off the Septra, after
having taken it for 8 days, 2x per day)
and God willing, we won't be faced with
severe side affects to my wife or our
unborn son (we haven't had any problems
yet, only minor nausea). I am
nevertheless frustrated at the hospital,
and regret not speaking up when my gut
told me to do so. The nurse didn't give
good enough evidence to us that the UTI
really existed - she was vague in telling
us that my wife had a UTI, and quickly
told us she was prescribing us Septra to
cure it. Now, unfortunately, I again have
to go back to not being able to trust yet
another group of people (nurses /
hospitals), as I had hoped to get away
from...
Patrick,
Sacramento, CA
BACTRIM:
29 November 2005
Hi
there Brian
I
had the worst experience of my life when
I was prescribed Bactrim for a sinus
infection. Twenty minutes after taking
this I felt my arms going numb and drove
myself to the local emergency room. By
the time I arrived there I could barely
get out of my car and had to be taken
inside in a wheelchair. I was unable to
even hold onto a phone! I was admitted
and had to be given potassium by IV since
my levels had dropped so low. I spent 3
days in the hospital from only ONE dose
of this stuff. The doctor could not
believe that this drug could do THAT to
me...........I was one of the RARE few
that this drug affects neurologically. I
not only lost strength in my hands and
legs but my heart at a resting state was
racing and my pulse was over 138 beats a
minute......(it normally is 64) After
being released I went to the local
chiropractor and did not tell him what
happened but told him of pains I was
experiencing through out my body ....I
told him I had pain even across my
face...........he said the only thing
that would cause the pain in my face was
from a toxic substance I must have
ingested!!!! Imagine that! I then told
him what had taken place.....I fear that
if I EVER had this drug again ..it would
indeed kill me!
One
thing I must add is that I am a very
physically fit individual and not
overweight etc. so for this to happen to
me really scared me. I hope anyone that
is given this, is aware of just how bad
things can get in a very short amount of
time..........I wish I had known!!!!!!!!!
Angel
R
BACTRIM:
29 November 2005
I
took Bactrim for bad skin infection on my
arm. The doctor said it was cellulitus. I
was told to take one tablet every 12
hours for 10 days even the condition is
all better. My skin condition was all
better by about 5 days later, but I kept
taking the medication. Through out the
course of medication, I started to have
vertigo and fatigue. I also felt
nauseous, too. On the 7th day in the
morning, I saw a hullucination as I saw
my landscaper in my yard. I saw him with
four arms! I blinked my eyes hard and
shook my head but my vision took more
than a few seconds to normalize. I went
right back to bed.
Suddently
on the 8th day in the morning as I was
eating a bowl of cereal, my right thigh
started to get very itchy. I looked at my
thigh and there were red and purple hives
all over my
thigh. I panicked and within a couple of
hours the hives spread all over my body.
I went to an emergency room and they told
me to stop taking it. That night, I had
chills and fever over 101. My joints were
in pain and I thought I was going to die.
Next
day, I went to my family doctor and she
took blood for a test. My white blood
cell count was very low. To treat the
condition, I was told to stop taking the
drug. Also, I was prescribed to take
METHYLPREDNISOLONE tablets (4mg). I took
them as I was told and I took a lot of
rest and ate a lot of vegitables, white
meat, garlic, and euchanatia tea. I got
all better in 2 - 3 days.
I
will never take this drug again. If you
have ANY concern is, if you think you
feel any of the symptom I described, stop
taking it and GO SEE A DOCTOR
immediately.
Anon
BACTRIM:
5 December 2005
Dear
Brian:
Thank
you for this website. My 66 year old
sister took a low dose course of Bactrim
for a UTI while traveling last month. She
had no apparent problems but the UTI
returned once she was back home in the
UK. She was then prescribed a high dose
of Trimethoprim alone. Within 2 hours of
taking the first dose, she started
getting the acute nausea, weakness and
headache associated with the Bactrim
reaction. She stopped taking the
Trimethorpim immediately, but it's now 4
days later and the headache has worsened,
the nausea is still bad, she's had the
fever and chills and is now so weak she
can't get out of bed. Doctor is coming
today. When she called the surgery two
days ago, they prescribed a cephalosporin
instead, but I've had an anaphylactic
reaction to those, so she doesn't want to
start on something that may cause more
problems. I'm the other side of the world
and, having read through your site, I am
really worried about her.
C
W
BACTRIM:
14 December 2005
Hello
Brian! Congrats on not only your
articulate and effective article, but
also on the courage you've shown by
producing it. I'd like to share a story
about Bactrim. I was diagnosed with a UTI
a week ago roughly, and was prescribed
Bactrim. The first day, I felt great, but
strange. This sounds weird, but it was
like I was in my own little world, and I
was extremely giggly. Well that ended
quickly. The second day, I noticed I felt
extremely tired and not in pain, but
stiff. My coordination was off and I
noticed right away, because I waitress in
the mornings, and I dropped things all
shift, and couldn't hold my focus.
I
was forgetting everything, and that's
very unusual. On the third day I woke up
and noticed my skin hurt. Nothing was
red, but it felt like a sunburn. I
actually couldn't sit on the toilet to
urinate because the seat hurt my skin. I
basically had to hover over it. I felt
like one big walking sore bruise. I don't
know why, but I never made anykind of
connection. You usually take what your
doctor gives you and you're good to go.
That, and I had never had any kind of
reaction to antibiotics in the past. Well
on both the 4th and 5th days of my
dosage, (2 tablets/day for 5 days) I
started getting shooting pains in my left
leg.
I
have a follow up appointment today, and I
am definitely planning on telling my
doctor about this. I have been freezing
(walking around w/ literally 3 pairs of
socks on) and my appitite was gone for
the whole time. I am getting that back
now. I don't understand why this drug is
still given, or why there hasn't been
more done about it. I commend you for
your efforts.
Sherry,
PA
SMZ-TMP:
14 December 2005
I
got cryptoccocal meningitus because my
immune system was suppressed due to my
having hemolytic anemia. I was put on a
multitude of drugs one of which was
SMZ-TMP. I came out of the hospital on
90mg of Prednisone, that was July 23,
2005. For approxiamately five weeks I've
been breaking out in a rash that has
continually gotten worse and itches
really bad. At this point I'm down to
20mg of Prednisone but the rash
practically covers my whole body. My
infectious disease doctor took me off the
SMZ-TMP yesterday thinking that might be
the culprit.
Lisa
C
SULFATRIM
DS: 15 December 2005
Mr.
Deer,
I
found your website as I was searching the
web for sulfatrim side-effects. I have to
admit it was really helpful since it
reveals accurate symptons and not only
theoritical side-effects.
Here's
my story. I am 27 years old and last
Thursday I consulted my doctor for a UTI
and he prescribed sulfatrim, twice a day
for 10 days. The next few days were not
that bad, my health seemed to improve. On
Tuesday night I started having chills and
I suddenly felt very tired. Then fever
appeared. Wednesday morning I noticed a
few red spots on my chest. At night
things had gone worse : fever, muscle
ache, extremely sensitive skin, red
ithchy spots from head to toe, serious
neck pain, swollen ganglions, a sore
throat, short breath, no energy at all
and backpain in the left kidney area.
I
went to the doctor today, he prescribed
complete rest for 5 days, had my blood
tested and I'm going back on Monday for a
check-up. Being aware of my health
background; I have been hospitalized for
left kidney infection last summer and my
mother suffers from severe kidney
problems...this worries me a little. The
side-effects of sulfatrim are absolutely
not worth the risks of taking this drug.
And since the side-effects are not
necessarily clearly stated, I consider
this drug very dangerous. Experiences
like mine and those of so many other
people cannot be left unsaid.
Thank
you,
Nancy
B
BACTRIM:
19 December 2005
Brian,
I wanted to share my experice because it
is different than most i have read on
your site. I had taken Bactrim straight
for about 2 years to clear up acne and
keep it away, this was the only thing
that worked for me( in combination with
Retin A and Benzoil peroxide ) I stopped
taking it because i didnt like the idea
of taking it all the time. , and
eventually my acne came back. I took it
again for another 2 years or so, and it
worked well again... eventaully i wanted
to stop taking it again... and back came
the large pimples. So once again i went
on it.. acne began to clear up but this
time i had side effects. I began to get a
bloody mucusy stool... it lasted a month
or so even after i stopped taking the
med. i also got a minor yeast infection
in my penis that went away away when i
stopped Batrim.. anyway i went to a GI
doc, he suggested that a diff type of bac
had taken over when the "good
bact" where killed inadvetantly..He
said it wouldnt make a diff if i
continued to take Bactrim so i stared
taking it again (i hate pimples) i got
tested for the other bactiria but, it was
not there,however i also stopped having
the sysmtoms by then.. and i started
taking Bactrim again at this time.. now
here i am still on bactrim and i have
what could be another side effect/.. the
past week or 2 i started gettin little
itchy bumps, kind of like poison ivy,
kind of like aquatic dermatosis... I
thought it was the second of the 2
because i go in the ocean alot, and have
had it.. anyway now i think it may be
from Bactrim...so im not sure what to
do!!!!!! ill let you know how it works
out...
john
BACTRIM:
20 December 2005
I
started taking this med last Wednesday
for a common sinus infection. I took two
each day until I woke up Sunday with
severe nausea. I have stopped taking it
but so far (this is early Tuesday
morning), no improvement. I'm also
beginning to be very very sore in most
joints.
Jan
S
BACTRIM:
21 December 2005
Hello,
i am a 20 yr old female, otherwise
healthy who was prescribed bactrim for a
sinus infection. I took 6 days worth and
then began to feel chills...tookanother
days worth and got hives... really really
itchy and cover me from head to toe
hives. I stopped taking the bactrim, but
at what point should i worry.
do
symptoms typically worsen from here.. ???
Dierdre
H
AP0-SULFATRIM:
22 December 2005
Hi
Brian,
I
just spent the past hour reviewing your
very interesting, informative site.
I
had a UTI a three weeks ago. Took
Apo-Sulfatrim for three days. After
taking the first pill, 15 mins later,
like hitting a brick wall, I experienced
the most intense vaginal itch ever. I
have heard before that yeast and bladder
infections go hand in hand and didn't
give it too much thought. Went back to
the pharmacy and purchased a 1 day
Canasteen application. I was surprised
though how strong and quick it came on.
Immediately
my bladder infection started to feel
better after the first antibiotic. The
vaginal itch continued for two more
straight days, keeping me up throughout
the night and bedridden, therefore
missing work. Finally on the eve of the
second day I called a pharmacist to get
their opinion as to whether the
antibiotic could be causing this and
whether I should retreat the yeast
infection. The response, continue the
antibiotics and if I don't feel any
better go to a doctor tomorrow. So on the
third and final day of the antibiotic
treatment I went to the see a doctor at a
clinic. To my surprise he told me to take
my last pill and to retreat the yeast
infection with a 6 day application. The
physician never did a physical exam.
Could not believe it! If he had he would
have know it was not a yeast infection. I
even spotted blood which I suspect came
from the intense irritation. I finished
the course of my pills and Canisteen and
within two days after the antibiotic, I
started to heal.
Nine
days after taking my last Apo-Sulfatrim
my bladder infection returned. After
struggling all day with it that eve I
took another antibiotic, and low and
behold the vaginal itch returned within
15 mins. Needless to say I did not take
another pill and I had my confirmation
that the itch was an adverse reaction. I
was in discomfort for three more days. I
was so angry especially with the
physician, as well as the Pharmacy
Pamphlet which neglected to highlight any
effects related to vaginal itch.
Three
weeks after taking my last pill, my GERD
is out of control. I am normally on
Pantoloc daily and that is making no
difference. My stomach is burning, it
feels like someone punched me and I am
nauseas. I suspect these symptoms are
remnants of the antibiotic. Do you have
any idea how long it takes to leave your
system?
Thanks,
Kellie
M. Ontario, Canada
SEPTRA:
22 Dec 2005
Hi,
my Dr prescribed Hydrochlorothiazide
which is a water pill for high blood
pressure last March I was told by the
pharmacist's that it contained Septra
which my Dr knows that I am very allergic
to, the pharmacist phoned my Dr as they
know that I am allergic to that drug and
there is a certain amount of Septra in
the drug I was told it was just a small
amount I was prescribed 25mg to be halfed
and half taken in the mornings a few
weeks later I developed burning sensation
in my legs and my tongue was covered with
ulcers it has gradually been getting
worse and now I have terrible sweats and
get really dizzy,feel very weak and
breathless my whole body feels its on
fire I have to be careful what I eat or I
get stomach pains I can't sleep at night
I feel frustrated and depressed as the Dr
can't tell me what is wrong with me.
sincerely,
Ailsa
S
SULFATRIM:
24 December 2005
To:
Brian Deer
I
often have bladder infection my Dr.
prescribed Cypro which worked very good
until the bacteria became immune to the
antibiotic,he then prescribed
APO-sulfatrim-DS after taking the first
dose my face started itiching my lip
broke out in what looked like a cold sore
and I had different rash spots on my face
and one eye after I stopped taking it
these side effects went away.It sure
was,nt fun.
Wayne
M
SEPTRA:
27 December 2005
I am
writing this email because I have never
experienced any allergic reaction in my
life to antibiotics. I have taken a few
doses of septra for a recurring UTI and
my entire body was covered in hives.
These hives were more like large welts,
and lasted for several days. As
uncomfortable as this rash and burning
itching was, I am more upset over the
terrible peeling scaling skin. I now have
patches on my chest, arm, lips, and chin.
No amount of moisturizers, Vaseline, or
creams seem to stop the peeling dry skin
and pain. Is there anything you can
suggest?
Melissa
C
SMZ/TMP:
28 December 2005
Dear
Brian,
My
husband was diagnosed with having a
prostate infection and POSSIBLY a urinary
tract infection. The doctor gave him ten
samples of Levaquin 750 mg. He also
prescribed Flomax .4mg in tablet form,
along with SMZ/TMP DS 800/160 to be taken
2x daily for 20 days. (to be taken after
the Levaquin was gone.)
He
started taking the septra on the 20th of
December, and continued taking the drug
for 5 days. On day 4, he started feeling
weak and had the all-over blahs . The
next day, he still had those symptoms,
along with loss of appetite, chills with
uncontrollable shakes, profuse sweating,
and inability to sleep even though he was
exhausted.
He
stopped taking the drug after I did some
research and came to your website. I was
appalled at what I read and angry at the
doctor who prescribed this to him. My
husband has already had two heart attacks
in his life; he doesn t need another. He
also takes meds for that, which makes me
wonder if the doctor even took that into
consideration. I m sure he did, but I
still wonder why he would prescribe
something that he most likely has no clue
about the side effects or he s one of
those that doesn t care, just wants his
money.
We
called the doctor back to inform him that
my husband was having these awful side
effects. His nurse called back to inform
us that they would call in a new
prescription, however, never even
bothered to ask what side effects he was
experiencing. She asked no questions nor
did she provide any other information.
The
new drug is Cephalexin 500 mg generic for
Keflex. I haven t done as much research
on this one yet, as my husband s not
going to take it until he starts feeling
better and getting over the effects of
the septra. Any information you can
provide on this drug will be greatly
appreciated.
Also,
I would like to know if you can offer up
some ways to get him feeling better
quicker. It s been two days now that he
has not taken the septra and is still
feeling ill.
Are
there certain foods or drinks he can take
that would help quickly? I ve got him on
ensure to at least replace lost vitamins
and minerals, but am having a hard time
getting him to drink lots of liquids or
eat anything.
Thanks,
Melinda,
Nashville, TN
SEPTRA:
30 December 2005
I
started septra 5 days later my tongue
started itching and swelling well the
next day when I woke up , my neck glands
looked like golf balls its been 4 days
since I have stoped taking the septra and
my toungue amd neck are getting worse I
am on aumentan for a sinus infection and
have been using this drug for years no
problems I know that septra has done
something to me is there a time frame for
the sulfites to leave ? this sucks I look
like someone with a tumor on my neck
Thanks for any help very painful
Tony
T
SEPTRA:
30 December 2005
Hello,
I
took Septra about two weeks ago for a UTI
and had no side effects. Then a week and
a half later I suddenly received a fever
that started off with a white tongue,
light sneezing that all disappeared
except for the fever. I have this fever
still and it is going on day 10. I do not
have any rashes. I feel hot on the top of
my back and on the top of my hands. My
normal body tempertature is 96- my fever
has been between 97.2-98.5. Could this be
the effects of Septra? Is there a way to
flush this out of my system completely
before it gets worse? I am 29 year old
female with no health problems. Thank you
Jenny
F
BACTRIM:
5 January 2006
Great
site. After having some nasty side
effects from this drug, I wonder in your
experience, what is the average time for
it to be flushed from one's system. I had
the typical itching, burning, dizzyness,
and now I have been off it for about
three days and still have numbness in my
feet and a sore back (which might not be
from the bactrim). It did knock out my
epydidimitis, but was a tough drug to
take.
Ryan
C, Fort Worth, Texas
SEPTRA:
6 January 2006
Hello:
When
my daughter was 3 years old, she started
getting recurring pneumonia, many drugs
were tried and tested. All of a sudden,
after a year and a half of pneumonia,
endless tests and tribulations, my
daughter's illness suddenly went away.
Relieved? No, it was the beginning of an
even worse nightmare. With each day that
passed, my daughter grew weaker and
developed a strange hue of skin.
I
took her back to her doctor who ordered
blood tests, my daughter needed an
immediate transfusion of packed red blood
cells or she would die. From then until
now, she is ten years old now, she has
needed monthly transfusions. The
specialists finally diagnosed her with
Acquired Red Cell Aplasia (Her bone
marrow was incapable of making red blood
cells.). I wondered and drove myself
nearly crazy trying to find out what
caused this. It was decided that the
antibiotics she was on for nearly two
years caused the bone marrow failure.
What drugs had she taken? Augmentin and
Septra. Was the treatment for the
pneumonia a life saver or a killer? Time
will tell, I just want people to be aware
of the many risks associated with these
drugs. Don't think this could never
happen to you or your family, that's what
I used to think.
Sincerely,
Jennifer
F
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